Modular oxygen measuring device for non-invasive optical oxygen measurements

Stand-along version of the modular oxygen measurement device available in a manually adjustable mount
© Fraunhofer IWS
Stand-along version of the modular oxygen measurement device available in a manually adjustable mount
Decline in 02 content in the glucose-oxidase catalyzed reaction of glucose to glucono-1,5-lactone
© Fraunhofer IWS
Decline in 02 content in the glucose-oxidase catalyzed reaction of glucose to glucono-1,5-lactone

A system for non-invasive measurement of oxygen concentrations was developed at the Fraunhofer IWS based on the OPAL System from Colibri Photonics GmbH in order to ascertain the uptake and consumption of oxygen in chemical, biochemical, and biological processes. Thanks to the compact 90 x 100 x 25 mm3 sensor head, the system can be adapted to operate as a stand-alone module or be employed as a measurement unit in a robotic portal. Automated, spatially-resolved measurement of oxygen content is possible by coupling it to the robotic portal system.


Principle of operation

  • measurement of oxygen content via fluorescence lifetime


Technical data

  • optical output power adjustable up to 1 W
  • data capture interval from 1 s to continuous, depending on the application
  • spatial resolution down to 500 µm
  • multiple measurements at programmed time intervals


Applications

  • spatially resolved monitoring of oxygen content in cell cultures
  • transducers in biosensors involving oxygen consumption
  • measurement of reaction kinetics for reactions involving oxygen consumption


Producer

  • Fraunhofer IWS